منابع مشابه
An Extraordinary Josephson Junction
The combination of symmetry breaking effects, such as those occurring in magnets and superconductors, with topological order may result in remarkable new physics. Recent theoretical studies suggest that, in certain superconductors, exotic quasiparticle excitations can emerge that behave like Majorana fermions, chargeneutral quasiparticles that are their own antiparticles. In Physical Review Let...
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We sought to determine the source of a norovirus outbreak among attendees of 46 weddings taking place during a single weekend. Norovirus-compatible illness was experienced by 332 (39%) of wedding guests surveyed; the outbreak affected up to 2700 persons. Illness was associated with eating wedding cake provided by a bakery common to the weddings (adjusted RR 4.5, P<0.001). A cake requiring direc...
متن کاملExtraordinary claims require extraordinary evidence.
At the beginning of 2003, the Journal of Health Economics published a paper of great importance in public policy by DiMasi, Hansen, and Grabowski (referred to hereafter as “DHG 2003”). The paper is based primarily on confidential, proprietary data supplied by pharmaceutical companies to the Tufts Center for the Study of Drug Development, a research center that receives significant unrestricted ...
متن کاملExtraordinary claims require extraordinary evidence
We thank Light and Warburton (2005) [hereafter LW] for providing a context for us to further discuss and clarify our studies on the cost of new drug development (DiMasi et al., 2003 [hereafter DHG]; DiMasi et al., 1991b [hereafter DHGL]; Hansen, 1979). We disagree, however, with their analyses, comparators, and conclusions. Although LW suggest, through the invocation of selected reported cost f...
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We have discovered that some weak uncouplers (typified by butylated hydroxytoluene) have a dynamic range of more than 10(6) in vitro: the concentration giving measurable uncoupling is less than one millionth of the concentration causing full uncoupling. They achieve this through a high-affinity interaction with the mitochondrial adenine nucleotide translocase that causes significant but limited...
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ژورنال
عنوان ژورنال: Anthrovision
سال: 2016
ISSN: 2198-6754
DOI: 10.4000/anthrovision.2237